V. Runkana, A. Pareek, P. Arora
Tata Consultancy Services, Pune, Maharashtra, India
Indian Institute of Technology Delhi, New Delhi, Delhi, India
Limited drug efficacy, undesirable temporal changes in drug concentration and patient non-compliance due to frequent dosing schedule have given impetus to design of controlled drug release systems . Biodegradable polymers due to their favorable and tunable properties and biocompatibility have found widespread use in the field of controlled drug delivery . Exploratory in vitro experiments ...
A. Warning , A. K. Datta ,
 Cornell University, Ithaca, NY, USA
The particle tracking model provided a deeper understanding to the experimental results. The model showed good agreement with experimental data for rotation, transport and attachment. In the attachment model, protrusions create low velocity, low shear regions increasing attachment while holes pull cells toward the surface and increase residence time on the surface increasing attachment rate.
V. Sharma , S. Pramanik , M. Mishra ,
 Indian Institute of Technology Ropar, Rupnagar, India
 Indian Institute of Technology Ropar, Rupnagar, India; Nordita, SE-10691 Stockholm, Sweden.
COMSOL Multiphysics® software was used to model radial source flow in two dimensional homogeneous porous media. Two-Phase Darcy's Law (tpdl) is used to model miscible viscous fingering. Fingering patterns obtained on using different mesh are discussed. Evolution from 'flowers' to 'branches' is observed in the fingering patterns. Stable displacement is generated even in the presence of unstable ...
B. Weber , D. Dauti , S. Dal Pont ,
 Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf, Switzerland
 Laboratoire 3SR, University Grenoble Alpes, Grenoble, France
When concrete is subjected to high temperature, capillary water evaporates and chemically bound water is released due to dehydration. This results in an increase of pore pressure, which is believed to be one of the mechanisms leading to spalling. Spalling of concrete is of high concern for the fire safety of concrete structures. We consider a model implemented in COMSOL® using the Weak Form ...
A. Kermani , N. Elabbasi 
 Veryst Engineering, Needham, MA, USA
Transdermal drug delivery (TDD) is used to deliver drugs through the skin as an alternative to oral, intravascular, and subcutaneous routes. While there are many advantages to TDD, skin is a very effective barrier and provides resistance to drug delivery. To improve drug delivery through the skin, permeation enhancers are used. We developed an axisymmetric COMSOL Multiphysics® software model ...
A.E. Varela, and J.C. García
University of Carabobo, Valencia, Venezuela
Most reactor designs are based on pseudo homogeneous models. This paper studies the COMSOL simulation of a packed bed reactor using a 2-D heterogeneous model. The case considered was a packed reactor with spherical catalyst for oxidation of o-xylene in air to phthalic anhydride. Large differences in intra-pellet temperature were found in comparison with the average temperatures resulting from ...
G. Zhang [1, 2, 3],
 Department of Bioengineering, Clemson University, Clemson, SC, USA
 Department of Electrical and Computer Engineering, Clemson, SC, USA
 Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC, USA
Implant devices are assistive devices surgically placed in the human body to restore the functionality of organs and tissues. Metallic implants are often used for load bearing applications including the hip and knee joints. To allow maximum flexibility during surgery for surgeons to pick and choose different combinations of parts (say, head, neck and stem, in the case of total hip replacement), ...
H. Zhu, T. Gulati, A. K. Datta, K. Huang
Institute of Applied Electromagnetics, Sichuan University, Chengdu, China
Department of Biological and Environment Engineering, Cornell University, Ithaca, NY, USA
Microwave drying of fruits and vegetables in a domestic oven has been found to result in large textural changes in the product such as puffing, crack formation and even burning due to the inhomogeneous heating of the microwaves. Microwave drying of potatoes is a complex interplay of mass, momentum and energy transport. Three phases are considered in the system: solid (skeleton), liquid (water) ...
Optimization of the Herringbone Type Micromixer Using Numerical Modelling and Validation by Measurements - new
E. Tóth, K. Iván, P. Fürjes
Pázmány Péter Catholic University, Budapest, Hungary
Research Centre for Natural Sciences Institute for Technical Physics and Materials Science Hungarian Academy of Sciences, Budapest, Hungary
COMSOL Multiphysics® software was used in this study to simulate mixing by diffusion and by secondary flow. Particle tracing model was applied to simulate the mixing of cells in the microchannel. Results agreed well with the measurement, an optimal herring-bone structure was proposed for integration into a bioanalytical system.
Modeling of Porous Catalyst Pellets: Comparison of Diffusion Flux Models for Steam Methane Reforming
P. L. Mills , L. Olabanji , A. Nagaraj , A. Nanduri ,
 Department of Chemical and Natural Gas Engineering, Texas A&M University - Kingsville, Kingsville, TX, USA
Introduction Steam reforming of natural gas has been the most common method for producing synthesis gas (CO + H2) for the production of H2, MeOH and NH3 for over half a century . Production of H2 in the USA using steam methane reforming (SMR) is ca. 9 MM tons/yr. Global production of NH3 using H2 derived from SMR was ca. 109 MM/yr in 2004. In the chemical industry, the SMR process is ...