Lowering of the Interstitial Fluid Pressure as a Result of Tissue Compliance Changes during High Intensity Focused Ultrasound Exposure: Insights from a Numerical Model
E. Sassaroli, B. O'Neill 
The Methodist Hospital Research Institute, Houston, TX, USA
Interstitial fluid pressure (IFP) is elevated in tumors. Owing to this elevated IFP, the interstitial fluid velocity (IFV) is negligible throughout the tumor but significant near the tumor margin. Any therapeutic strategy that can lower IFP will improve drug convection within the tumor and decrease convection of drugs from the tumor margin. High intensity focused ultrasound (HIFU) has been shown ...
S. Hoyer, M. Bottig, F. Zekiri, G. Götzl, A.K. Brüstle, G. Schubert, A. Nador
Geological survey of Austria, Vienna, Austria
Geological Institute of Hungary, Budapest, Hungary
Temperature measurements of the subsurface are available due to hydrocarbon exploration in the project area, where the average drilling depth is about 2-4 km and the deepest well reaches about 8.5 km. Since the data is heavily uneven distributed, standard interpolation techniques did not deliver satisfying results. This is why numerical modeling was applied to assess the thermal regime of the ...
Indian Institute of Technology Madras, Chennai, Tamil Nadu, India
Realising the interlinkage of nature and engineering are of paramount essential while comprehending the basics of system’s performances. Application of biotechniques in air pollution control is one such emerging scientific area, where the understandings of these complex systems demand more utilisation of computing softwares. Recently, biofiltration is a versatile biological air pollution control ...
A.R. Sánchez-Guitard, E. Ruiz-Reina
University of Málaga, Málaga, Spain
In this work, we study the design of a new integrated system for Solar Water Heating that combines the solar thermal energy collection (primary circuit) with the heat storage (secondary circuit) into the same device. We have performed different finite element method simulations using COMSOL Multiphysics®, for solving the equations of heat transfer (conduction and convection) and those of fluid ...
K. Cluff, H. Mehraein, B. Jayakumar
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA
Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment intervention some PAD patients require follow up secondary treatment due to a continued decline in limb function, ...
Materials Synthesis & Integrated Devices, Los Alamos National Laboratory, Los Alamos, NM, USA
Oil and water are immiscible fluids and they tend to separate very easily when introduced into a flow stream from two different sources in a flow loop. This model studies the development of mixture volume fraction in an oil-water-flow loop with 3 different passive mixing schemes: (i) blind-T, (ii) check valve, and (iii) static mixer. Each device produces different levels of mixture homogeneity ...
Can we use Aquifers to Monitor Magma Chambers? Using COMSOL Multiphysics® to Investigate Subsurface Strain Changes and Their Effect on Hydrological Systems - new
K. Strehlow, J. Gottsmann, A. Rust
University of Bristol, Bristol, UK
Groundwater-bearing geological layers respond to and modify the surface expressions of magmatic activity, and they can also become agents of volcanic unrest themselves. Interpretations of unrest signals as groundwater responses to changes in the magmatic system can be found for many volcanoes and include a wide range of phenomena and suggested processes to explain them (e.g., Newhall et al., ...
Modelling of the Dynamical Fluorescent Micro-Thermal Imaging Experiment on the Heat Diffusion in the La5Ca9Cu24O41 Spin Ladder Compound - new
E. Khadikova, F. de Haan, P. H. M. van Loosdrecht
Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands
Department of Physics, University of Cologne, Köln, Germany
The dynamical fluorescent micro-thermal imaging (FMI) experiment has been used to investigate the phonon-magnon interaction in the 1D Heisenberg antiferromagnet La5Ca9Cu24O41. This material shows highly anisotropic heat conductivity due to the efficient magnetic heat transport along the spin ladders in the compound carried by magnetic excitations (magnons). To extract information on the phonon ...
Modeling and Simulation of High Sensitivity CMOS Pressure Sensor Using Free Boundary Circular Diaphragm Embedded on Ring Channel Shaped MOSFET
S. Joy, T. Tom
Rajagiri School of Engineering and Technology, Kochi, Kerala, India
Sensors have diverse applications ranging from medical field to space explorations. They convert physical parameters such as temperature, pressure, humidity etc: - into an electrical output. The discovery of piezoresistivity property of silicon and germanium led to miniaturization of pressure sensors. Improvement in the sensitivity is the major factor to be considered while designing pressure ...
P. Qian [1, 2],
 University of Wisconsin - Madison, Madison, WI, USA
 SmartUQ, Madison, WI, USA
Uncertainty appears in many aspects of physical simulations including stochastic design parameters, hard-to-specify input distributions, probabilistic boundary and initial conditions, and unknown geometries. Uncertainty Quantification (UQ) has emerged as the science of quantitative characterization and reduction of uncertainties in both simulation and test results. Stretching across applied ...