J. G. Immanuel, K. Poojitha, B. Viknesshwar, A. Gupta
PSG College of Technology, Peelamedu, Coimbatore, Tamil Nadu, India
The paper brings out the designing and implementation of blood viscosity monitoring device that gives us the INR to measure the effectiveness of anti coagulant medications .When a blood vessel is damaged, clotting cascade begins that results in blood clot. This process is affected by several medical conditions where it becomes mandatory for a patient to intake anti-coagulants. Thus to monitor ...
N. Das, C. R. Chaudhuri
Department of Electronics and Telecommunication, BESUS, Howrah, West Bengal, India
In this paper, we have proposed an impedance biosensor based on polymer nanowire (made of polyaniline) for efficient electric field mediated capture of biomolecules. Existing polymer nanowire based biosensors fail to achieve high sensitivity for low surface to volume ratio as the whole length of the nanowire is exposed to the analyte .Also biosensors are dependent on diffusion mediated capture ...
L. Wright, G. Memoli, P. Jones, E. Stride
National Physical Laboratory, Teddington, UK
University College London, London, UK
University of Oxford, Oxford, UK
Understanding the interactions between microbubbles and surfaces is key to the successful deployment of microbubbles in a range of applications. Two important examples are their use as a drug delivery mechanism, and their potential use of acoustically-driven bubbles as microscale sensors. Drug delivery with bubbles involves sonication at high frequency close to a boundary, and sensing with ...
K. Misiunas, N. Laohakunakorn, S. Ghosal, O. Otto, U. F. Keyser
University of Cambridge, Cambridge, UK
Northwestern University, Evanston, IL, USA
The motion of DNA in crowded environments is a common theme in physics and biology. Examples include gel electrophoresis and the self-interaction of DNA within cells and viral capsids. Here we study the interaction of multiple DNA molecules within a nanopore by tethering the DNA to a bead held in a laser optical trap to produce a "molecular tug-of-war". We measure this tether force as a function ...
A. G. S. Barreto Neto , A. M. N. Lima , C. S. Moreira ,
 Instituto Federal de Ciência e Tecnologia - IFPB, João Pessoa, PB, Brasil
 Universidade Federal de Campina Grande - UFCG, Campina Grande, PB, Brasil
Este trabalho trata do dimensionamento da estrutura bocal/difusor utilizando a simulação computacional com fronteira móvel. Esse tipo de simulação contempla toda estrutura da bomba, isto é, câmara de bombeamento, difusor e área de dispersão de fluxo, de modo a contabilizar o refluxo em função da estrutura, possibilitando um projeto mais realísticos da estrutura.
Study of Fluid and Mass Adsorption Model in the QCM-D Sensor for Characterization of Biomolecular Interaction
H.J. Kwon, C.K. Bradfield, B.T. Dodge, and G.S. Agoki
Department of Engineering and Computer Science, Andrews University, Berrien Springs, Michigan, USA
Increasing attention has been paid to application of the quartz crystal microbalance with dissipation (QCM-D) sensor for monitoring biomolecular interactions. This paper focuses on a practical application of protein-protein binding affinity measurement at low concentrations and minimal sample sizes (50-200 μl of 20-200 nM), which results in low signal measurement. A model simulating fluid ...
D. Kappe, A. Hütten
University of Bielefeld, Bielefeld, Germany
The possibility to detect and probe molecules in microfluidic devices gives rise to interesting applications. There are different approaches how to detect and probe particles, but a common step, for most methods, is to place the particles on a sensor. This can be done by applying external field gradients, or in this case by utilizing gravitational and hydrodynamic effects. Therefore, the sensor ...
A. Ivanov, U. Mescheder
Furtwangen University, Furtwangen, Germany
In the presented work the dynamic simulation of a silicon anodization process is performed. Two mechanisms of etch form development (diffusion in electrolyte, current flow) are considered and simulated. Influence of electrolyte conductivity and radius of the opening in the masking layer is discussed.
V. Tiwari, R. Sharma, G. Srivastava, R. Dwivedi
Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India
Cantilever beam-type transducers have been in great demand and explored widely in the recent years, typically in thin film form because of their sensor and actuator applications. The piezoelectric cantilever is the most preferred structure employed in technological applications. Depending on the required flexural motion and sensitivities, these piezoelectric cantilevers can be used in unimorph, ...
3D-Modeling of Magnetophoretic Separation of Superparamagnetic Dispersions Using COMSOL Multiphysics® Particle Tracing Module
D. Kleinehanding, L. Teich, C. Schröder
Department of Engineering Sciences and Mathematics, Computational Materials Science & Engineering (CMSE), University of Applied Sciences Bielefeld, Bielefeld, Germany
Magnetophoresis is a process of great interest for novel applications based on magnetic nanoparticles and colloids. Environmental applications like wastewater treatments and pollutant removal, biomedical applications like protein isolation, drug delivery, magnetic hyperthermia for cancer treatment, and magnetic-particle imaging are just a few of the numerous technological areas which exploit the ...