Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Laser Interstitial Thermo Therapy (LITT) for Prostate Cancer Animal Model: Numerical Simulation of Temperature and Damage Distribution

M.F. Marqa, P. Colin, P. Nevoux, S. Mordon, and N. Betrouni
University of Lille, CHRU, Lille, France

Laser interstitial thermotherapy (LITT) is a cancer treatment technique in which laser fibers are introduced inside the tumor. While it destroys deep tumors, the LITT procedure allows minimizing the impact on adjacent healthy structures. One of the effective methods to perform treatment planning for LITT is simulation. We used COMSOL Multiphysics to simulate the heat distribution and thermal ...

An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging

G.R. Cook[1], M.J. Graves[1], F.J. Robb[2], D.J. Lomas[1]
[1]Department of Radiology, University of Cambridge, Cambridge, United Kingdom
[2]General Electric Healthcare Coils, Aurora, Ohio, USA

MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...

Modeling Bioclogging Effects in Constructed Wetlands for Wastewater Treatment - new

R. Samso[1], N. Forquet[2], P. Molle[2], J. Garcia[1]
[1]Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
[2]IRSTEA, Freshwater Systems, Ecology and Pollution Research Unit, Villeurbanne, France

Horizontal-Flow Constructed Wetlands (HFCWs) are a particular type of biofilter, and as such they rely mostly on the activity of bacterial communities to treat wastewater. Bacterial growth in HFCWs induces dramatic changes in its hydraulic and hydrodynamic behaviour (bioclogging), which may eventually result in overland flow of wastewater. Consequently, clogging is the main cause of premature ...

Computational Design and Optimization of Bone Tissue Engineering Scaffold Topology

N. P. Uth [1], J. Mueller [2], B. Smucker [3], A. Yousefi [1],
[1] Department of Chemical, Paper, and Biomedical Engineering, Miami University, Oxford, OH, USA
[2] Research Computing Support, Miami University, Oxford, OH, USA
[3] Department of Statistics, Miami University, Oxford, OH, USA

Introduction: Bone tissue has a limited ability for regeneration; critically sized defects cannot self-heal and require medical intervention. Bone tissue engineering (TE) circumvents this issue by growing replacement bone tissue from the patient’s own cells inside scaffolds. TE scaffolds are porous constructs that act as a support structure during bone regeneration and helps cells attach and ...

Simulating Organogenesis in COMSOL Multiphysics®: Tissue Mechanics during Organ Growth

M. Peters [1], D. Iber [1],
[1] D-BSSE, ETH, Zurich, Switzerland

During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of tissues. On long time scales, as characteristic for many developmental processes, tissue is therefore typically represented as a liquid, viscous material and ...

Numerical Simulation of the Functional Electromagnetic Stimulation of the Human Femoral Bone using COMSOL

Y. Haba[1], W. Kröger[2], H. Ewald[2], R. Souffrant[1], W. Mittelmeier[1], and R. Bader[1]

[1]Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, University of Rostock, Rostock, Germany
[2]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany

In the present study we determined the relative conductivities and permittivities of fresh cortical and cancellous bone measuring human femoral heads in different slices of 1 mm thickness. The identified conductivities of human trabecular bone are used for the electromagnetic field simulation by means of COMSOL using a Micro-Computed Tomography (Micro-CT) model. The calculated model depends on a ...

Modeling Arterial Drug Transport From Drug-eluting Stents: Effect of Blood Flow on the Concentration Distribution Close to the Endothelial Surface

F. Bozsak, J.-M. Chomaz, and A. I. Barakat
LadHyX, Ecole Polytechnique
Palaiseau, France

Drug-eluting stents (DES) are commonly used for treating coronary atherosclerosis. Despite the broad effectiveness of DES, ~5% of treated patients experience complications including in-stent restenosis and late-stent thrombosis. Furthermore, drugs used in DES not only inhibit proliferation of smooth muscle cells but also affect re-endothelialization. We have developed a computational model ...

A Study on Nutrient Mass Transport through Porous Channeled Flat Sheet Membrane and Prediction of Maximum Scaffold Thickness for Viable Cell Culture (In-vitro) by 3D Modeling for Tissue Engineering Application

N. M. S. Bettahalli[1], B. J. Papenburg [2], D. S. Stamatialis [2], M. Wessling [3]
[1]University of Twente, Enschede, The Netherlands & BMS College of Engineering, Bangalore, India
[2]University of Twente, Enschede, The Netherlands
[3]RWTH Aachen University

Tissue engineering (TE) is a multidisciplinary field involving principles of engineering and life sciences to improve the health and quality of life by repairing, restoring, maintaining, or enhancing tissue and organ function using cells, scaffolds, and growth factors alone or in combination. There are several artificial tissues that are already being used which include fabricated skin, ...

Shear Stress Analysis in High-Throughput Dual-micropillar-based Microfluidic Platform

J.Borana[1], J.M.Lee[2], B.G.Chung[2]
[1]Indian Institute of Technology Guwahati, Guwahati, India
[2]Department of Mechanical Engineering, Sogang University, Seoul, Korea

We developed the dual-micropillar-based microfluidic platform to control cellular behavior. The 4×4 dual micro-pillar based platform consists of 16 circular-shaped outer micropillars and 8 saddle shaped inner-micropillars. We simulated various shapes of inner micropillars to analyze the shear stress inside the inner micropillar. Therefore, this dual-micropillar-based microfluidic platform could ...

Fresh Produce Safety During Hydrocooling: An Engineering Model - new

A. Warning[1], A. K. Datta[1]
[1]Department of Biological & Environmental Engineering, Cornell University, Ithaca, NY, USA

Hydrocooling is the process by which warm produce is chilled with water. The chilling of warm produce generates a negative pressure differential between the produce (warm) and (cold) water due to the condensation of water vapor inside the produce which forms a vacuum and can pull in contaminated water through an opening. A porous media based model of water infiltration was developed using a ...